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Revisiting the Age-Old Concepts on 'Acid-Peptic-Disorders'

Dr. Vijay Singh Chauhan, Dr. Naresh Khemani

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The basic on which our Antacid/Antiulcerant Formulation is Designed

Considering that the treatment of ulcer is not merely acid control, following other factors have also been given due consideration while formulating this product:
  • Acid reduction.
  • Reduction in the intensity of pain
  • Improving digestive process
  • Promoting healing and repair
While selecting the ingredients, following points have to be considered thoroughly.
(1) Acid reduction is essential in all the cases.
(2) All the ulcer patients particularly those suffering from gastric ulcers may be hyperacidic.
(3) Acid pH should not be changed till the point of achlorhydria in vulnerable cases.
Unlike H2 blockers and antacids there should be other complementary ingredients to take care of other disturbing factors.

Acid Control

Excessive gastric acid and pepsin secretion is one of the major causes behind ulceration. This hyper-acid secretion needs to be controlled immediately as it may worsen the condition.

Reduction in the Intensity of Pain

Irritation of the gastric mucosa by acids results into pain which is characterized as ‘burning’, ‘gnawing’, ‘discomfort’, ‘dull ache’, ‘gas’, etc. Pain is such a symptom, that with presence of it, a person feels very uncomfortable and diseased. Pain factor is usually overlooked in ulcer-treatment which is very important as far as complete ulcer-treatment is concerned.

Promotion of Healing and Repairs of Damaged Mucosal Cells

Besides controlling hyperacidity, building up defensive factors i.e. gastric barrier is important area. Hence the elements that protect the gastric epithelium from the injury should be a part of the treatment.

Improving Digestive Process

It is possible that with gastric irritation the whole digestive process could get disturbed. Hence, the digestive functioning has to be improved.

Some of the Acclaimed Herbs are being Mentioned here for the users’ Reference:

(1) Indian Name: Amalaki / Amla
English Name: Embelic Myrobalan
Botanical Name: Emblica officinalis / Phyllanthus emblica
Parts Used: Dried fruits.

Phytochemistry: The fruit is a rich source of Ascorbic acid (Vitamin C) 10 gms of fresh fruits contain 700-1000 mg of Vitamin C. The small fruit variant contains more Vitamin C than the larger variant. Ellagic acid is present in the bark and fruits. Fruits also contain gallic acid, glucose, pectin and tannin which is responsible for the stability of ascorbic acid content.

Ayurvedic Properties: Guna: Laghu, Ruksha; Rasa: All rasas present except Lavana; Veerya: Sheeta; Vipaka: Madhura; Dosha: Tridoshahara; Karma: Rasayana, Pramehaghna, Shukrala, Deepana, Keshya, Medhya, Chakshushya, Anulomana.

Clinical Usage: Emblica officinalis is useful in both in acid-peptic ulcer and non-ulcer dyspesia.

It is considered as one of the foremost Rasayana (Rejuvenator and Immuno-modulator) drugs imparting a long healthy life and weight gain. Besides, Amla is also known for its healing and repair action, cholagogue and correction of metabolic errors. Improved haematological picture and diminished E.S.R. are also observed. The dried fruit powder applied to hair and skin form increasing hair growth and lustre.

The fruit of Emblica officinalis is commonly used as a tonic especially in winter season in India. The leaf is used in conjunctivitis, bronchitis and leucorrhoea. The juice of the fresh bark with honey and turmeric is given in urinary infections.

Pharmacology (Extra): Alcoholic extract of the plant (1 gm/kg) has shown decrease in serum GOT, GPT and LDH in isoprotenol pretreated rats, suggesting a cardio-protective action. It showed the reduction in serum cholesterol level and exerts antiatherogenic effects. Studies suggest that Vitamin C alone may alone not be responsible for such activity but it should be the collective effect of group of Phytochemical constituents.

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